中文版 | English
CSpace  > 生态毒理学研究中心
Toxicity and oxidative stress induced by chromium in workers exposed from different occupational settings around the globe: A review
Junaid, Muhammad1,2,3; Hashmi, Muhammad Zaffar4; Malik, Riffat Naseem2; Pei, De-Sheng3
2016-10-01
摘要The present review focused on the levels and toxicological status of heavy metals especially chromium (Cr) in the exposed workers from different occupational settings around the globe and in Pakistan. It was found that exposed workers from leather tanning and metal plating units showed elevated levels of Cr than the workers from other occupational settings. Cr and other heavy metals level in biological matrices of the exposed workers in different occupational settings revealed that developing countries are severely contaminated. Occupational settings from the Sialkot district, Pakistan exhibited elevated level of Cr in biological entities of the exposed workers. Review suggested that higher level of Cr exposure to the workers enhance the oxidative stress (reactive oxygen species (ROS) and hydroxyl (OH) radical generation) which may cause; cellular and molecular damage such as genotoxicity and chromosomal aberration formations, and carcinogenic effects. This review will help to understand the Cr contamination mechanisms and associated health implications in different occupational settings around the globe in general and particularly to Pakistan. This study will also assist occupational health and safety management authorities to devise or change the Cr recommended exposure limits (REL) for different occupational settings.
关键词Workers Chromium Occupational setting Oxidative stress Cr toxicity
DOI10.1007/s11356-016-7463-x
发表期刊ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
ISSN0944-1344
卷号23期号:20页码:20151-20167
通讯作者Malik, RN (reprint author), Quaid I Azam Univ, Fac Biol Sci, Dept Environm Sci, Environm Biol & Ecotoxicol Lab, Islamabad, Pakistan. ; Pei, DS (reprint author), Chinese Acad Sci, Chongqing Inst Green & Intelligent Technol, Res Ctr Environm & Hlth, Chongqing 400714, Peoples R China. ; Hashmi, MZ (reprint author), COMSATS Inst Informat Technol, Dept Meteorol, Islamabad, Pakistan.
收录类别SCI
WOS记录号WOS:000387599100010
语种英语