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Discovery of novel Thymol-TPP antibiotics that eradicate MRSA persisters 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 270, 页码: 15
作者:  Tang, Ziyi;  Feng, Jizhou;  Challa, Mahesh;  Rowthu, Sankara Rao;  Xiong, Shuxin;  Zou, Cheng;  Li, Jianguo;  Verma, Chandra Shekhar;  Peng, Haibo;  He, Xiaoli;  Huang, Chao;  He, Yun
收藏  |  浏览/下载：14/0  |  提交时间：2024/07/12
Antibacterial  Thymol  Triphenylphosphonium (TPP)-conjugates  Persister  
Isolation of Extracellular Outer Membrane Vesicles (OMVs) from Escherichia coli Using EVscore47 Beads 期刊论文
MOLECULES, 2024, 卷号: 29, 期号: 8, 页码: 14
作者:  Shi, Gongming;  Yang, Xiaohong;  Wang, Jikai;  Wei, Wenjing;  Hu, Kecui;  Huang, Xingyue;  Qiu, Yanfei;  He, Yun
收藏  |  浏览/下载：8/0  |  提交时间：2024/07/12
multifunctional chromatography microspheres  purification  outer membrane vesicles  
Development of membrane-targeting TPP+-chloramphenicol conjugates to combat methicillin-resistant staphylococcus aureus (MRSA) infections 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 264, 页码: 13
作者:  Li, Tao;  He, Xiaoli;  Tao, Wenlan;  Zhang, Ruixue;  He, Qiaolin;  Gong, Hongzhi;  Liu, Ye;  Luo, Dong;  Zhang, Maojie;  Zou, Cheng;  Zhang, Shao-Lin;  He, Yun
收藏  |  浏览/下载：22/0  |  提交时间：2024/02/23
Triphenylphosphonium cation  Membrane disruption  Drug-resistance  
Recent Advances and Techniques for Identifying Novel Antibacterial Targets 期刊论文
CURRENT MEDICINAL CHEMISTRY, 2024, 卷号: 31, 期号: 4, 页码: 464-501
作者:  Nazli, Adila;  Qiu, Jingyi;  Tang, Ziyi;  He, Yun
收藏  |  浏览/下载：23/0  |  提交时间：2023/12/25
Antibacterial  omics  machine learning  bioinformatics  drug target  bacterial cytological profiling  
2,4-Diacetylphloroglucinol (DAPG) derivatives rapidly eradicate methicillin-resistant staphylococcus aureus without resistance development by disrupting membrane 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 261, 页码: 18
作者:  Zhong, Yifan;  He, Xiaoli;  Tao, Wenlan;  Feng, Jizhou;  Zhang, Ruixue;  Gong, Hongzhi;  Tang, Ziyi;  Huang, Chao;  He, Yun
收藏  |  浏览/下载：21/0  |  提交时间：2023/12/25
4-Diacetylphloroglucinol  MRSA  Antimicrobial resistance  Cell membrane  Synergy  Biofilm  
Uncovering the anti-biofilm activity of Ilicicolin B against Staphylococcus aureus 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2023, 卷号: 684, 页码: 8
作者:  Tang, Ziyi;  Feng, Jizhou;  Rowthu, Sankara Rao;  Zou, Cheng;  Peng, Haibo;  Huang, Chao;  He, Yun
收藏  |  浏览/下载：27/0  |  提交时间：2023/12/25
Ilicicolin B  Antibacterial  Anti-biofilm activity  Extracellular polymeric substances (EPS)  Staphylococcus aureus  
Design and evaluation of tadpole-like conformational antimicrobial peptides 期刊论文
COMMUNICATIONS BIOLOGY, 2023, 卷号: 6, 期号: 1, 页码: 14
作者:  Tang, Ziyi;  Jiang, Wuqiao;  Li, Shuangli;  Huang, Xue;  Yang, Yi;  Chen, Xiaorong;  Qiu, Jingyi;  Xiao, Chuyu;  Xie, Ying;  Zhang, Xu;  Li, Jianguo;  Verma, Chandra Shekhar;  He, Yun;  Yang, Aimin
收藏  |  浏览/下载：23/0  |  提交时间：2023/12/25
Facile and stereospecific synthesis of diverse β-N-glycosyl sulfonamide scaffolds via palladium catalysis 期刊论文
CHEMICAL COMMUNICATIONS, 2023, 卷号: 59, 期号: 86, 页码: 12907-12910
作者:  Zhong, Lei;  Wang, Qunliang;  Wang, Yujuan;  Cheng, Yiyang;  Xiong, Yimeng;  Peng, Haibo;  Zhou, Zhen;  He, Yun;  Dai, Yuanwei
收藏  |  浏览/下载：22/0  |  提交时间：2023/12/25
Functionalized human umbilical cord mesenchymal stem cells and injectable HA/Gel hydrogel synergy in endometrial repair and fertility recovery 期刊论文
ACTA BIOMATERIALIA, 2023, 卷号: 167, 页码: 205-218
作者:  Zhang, Donghai;  Du, Qianqian;  Li, Cong;  Ding, Chuanfeng;  Chen, Junfeng;  He, Yun;  Duan, Tao;  Feng, Qian;  Yu, Yongsheng;  Zhou, Qian
收藏  |  浏览/下载：20/0  |  提交时间：2023/12/25
Hydrogel  Endometrial injury  Hyaluronic acid  Gelatin  Human umbilical cord mesenchymal stem  cells  
Optimization of the Natural Product Calothrixin A to Discover Novel Dual Topoisomerase I and II Inhibitors with Improved Anticancer Activity 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 11, 页码: 8040-8061
作者:  Yang, Xiaohong;  Wang, Zhi-Peng;  Xiang, Sichuan;  Wang, Daoqiang;  Zhao, Yi;  Luo, Dong;  Qiu, Yanfei;  Huang, Chao;  Guo, Jian;  Dai, Yuanwei;  Zhang, Shao-Lin;  He, Yun
收藏  |  浏览/下载：47/0  |  提交时间：2022/08/22